COVID-19-Related Potential Multisystem Inflammatory Syndrome in Childhood in a Neonate Presenting as Persistent Pulmonary Hypertension of the Newborn
Rekha Khaund Borkotoky, Puja Banerjee Barua, Siba Prosad Paul, Paul Anthony Heaton
Abstract
A term infant with persistent pulmonary hypertension of newborn developed clinical and laboratory features of multisystem inflammatory syndrome in childhood (MIS-C) between days 12 and 14. Mother and baby were anti-SARS-Coronavirus-2 (SARS-CoV-2) IgG positive and anti-SARS-CoV-2 IgM negative on day 18, with negative COVID-19 PCR on repeated testing; possible first documentation of neonatal MIS-C following passive transfer of maternal antibodies.
Topics & Concepts
MedicineCoronavirus disease 2019 (COVID-19)Persistent pulmonary hypertensionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pulmonary hypertension2019-20 coronavirus outbreakPediatricsAntibodyImmunologyVirologyInternal medicineDiseaseInfectious disease (medical specialty)OutbreakKawasaki Disease and Coronary ComplicationsCOVID-19 Impact on ReproductionCardiovascular Issues in Pregnancy