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Epithelial cells remove precancerous cells by cell competition via MHC class I–LILRB3 interaction

Shiyu Ayukawa, Nagisa Kamoshita, Jun Nakayama, Ryohei Teramoto, Novalia Pishesha, Kenji Ohba, Nanami Sato, Kei Kozawa, Hikari Abe, Kentaro Semba, Nobuhito Goda, Yasuyuki Fujita, Takeshi Maruyama

2021Nature Immunology46 citationsDOI

Topics & Concepts

Cell biologyMHC class ICytotoxic T cellMajor histocompatibility complexBiologyCD8Immune systemChemistryImmunologyGeneticsIn vitroImmune Cell Function and InteractionCAR-T cell therapy researchT-cell and B-cell Immunology
Epithelial cells remove precancerous cells by cell competition via MHC class I–LILRB3 interaction | Litcius