Epitranscriptomic control of cancer hallmarks: Functions, mechanisms, and therapeutics of RNA modifications
Xiaolan Deng, Dong Wu, Yingqi Zhao, Ying Qing, Huizhe Wu, Jianjun Chen, Jianjun Chen
Topics & Concepts
RNABiologyPseudouridineCancerComputational biologyCancer cellRNA-binding proteinCell biologyRNA interferenceCellRegulation of gene expressionHEK 293 cellsmicroRNAGeneTranslational regulationCancer researchGene expressionGeneticsSignal transductionRNA silencingBioinformaticsNucleic acid structurePost-transcriptional regulationTranslation (biology)N6-MethyladenosineTargeted therapyMessenger RNACRISPRCancer therapySmall hairpin RNARegulatorSystems biologyCompeting endogenous RNACell growthRNA modifications and cancerRNA regulation and diseaseMetalloenzymes and iron-sulfur proteins