In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies
Eman A. Fayed, Yousry A. Ammar, Ahmed Ragab, Nirvana A. Gohar, Ahmed B. M. Mehany, Amel M. Farrag
Topics & Concepts
ChemistryADMEApoptosisCytotoxic T cellCell culturePharmacologyCell cycleIn vitroThiazoleCell cycle checkpointImatinibCytotoxicityCancer cellCancerCancer researchBiochemistryStereochemistryInternal medicineMyeloid leukemiaBiologyGeneticsMedicineSynthesis and Biological EvaluationSynthesis and biological activityQuinazolinone synthesis and applications