Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
Marie Lagouge, Carmen Argmann, Zachary Gerhart‐Hines, Hamid Méziane, Carles Lerín, Frédéric Daussin, Nadia Messadeq, Jill C. Milne, Philip Lambert, Peter J. Elliott, Bernard Gény, Markku Laakso, Pere Puigserver, Johan Auwerx
Topics & Concepts
ResveratrolMitochondrial biogenesisBiologyOxidative phosphorylationMitochondrionSirtuin 1Energy homeostasisRegulatorAcetylationHomeostasisActivator (genetics)PhosphorylationCell biologyInsulin resistanceEndocrinologyBiochemistryInsulinGeneDownregulation and upregulationObesitySirtuins and Resveratrol in MedicineAdipose Tissue and MetabolismBiochemical effects in animals