A ratiometric fluorescent probe for imaging enzyme dependent hydrogen sulfide variation in the mitochondria and in living mice
Yuming Zhang, Yuncong Chen, Hongbao Fang, Xiangchao Shi, Hao Yuan, Yang Bai, Weijiang He, Zijian Guo
Abstract
CouDE could monitor the endogenous H<sub>2</sub>S level change induced by alteration of CBS enzyme activity in living cells and <italic>in vivo</italic>.
Topics & Concepts
Hydrogen sulfideFluorescenceEndogenyIn vivoEnzymeMitochondrionChemistryBiophysicsEnzyme assayBiochemistryCell biologyBiologyPhysicsGeneticsOpticsOrganic chemistrySulfurSulfur Compounds in BiologyMolecular Sensors and Ion DetectionEicosanoids and Hypertension Pharmacology