PO<sub>3</sub>H<sub>2</sub>-Functionalized Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> Core–Shell as an Efficient and Magnetic Nanocatalyst for the Preparation of Dihydropyrimidinones <i>via</i> Biginelli Condensation
Leila Pirhadi, Alana M. M. Rangaswamy, Ebrahim Soleimani
Abstract
Fe3O4@SiO2 phosphonic acid nanoparticles are prepared to perform as a new and reusable acid catalyst for the one-pot synthesis of Biginelli products. One of the unique advantages of the catalyst is its simple and convenient synthesis, and that it is certified based on the results of FT-IR, XRD, TGA, TEM, SEM, EDX and VSM analysis. The catalyst may be recovered from the reaction mixture through the application of an external magnet and was found to be capable of repeated reuse without significant loss of activity.
Topics & Concepts
ChemistryCatalysisNuclear chemistryNanoparticleSolid acidChemical engineeringNanotechnologyOrganic chemistryMaterials scienceEngineeringMulticomponent Synthesis of HeterocyclesSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds