Identification of T-cell exhaustion-related genes and prediction of their immunotherapeutic role in lung adenocarcinoma
Chaoqun Lian, Feifan Li, Yiluo Xie, Linxiang Zhang, Huili Chen, Ziqiang Wang, Xinyu Pan, Xiaojing Wang, Jing Zhang
Abstract
The TEX model showed good predictive performance and provided a new perspective for evaluating the efficacy of preimmunization, which provides a new strategy for the future treatment of lung adenocarcinoma.
Topics & Concepts
GeneUnivariateProportional hazards modelImmunotherapyAdenocarcinomaLung cancerComputational biologyBiologySurvival analysisOncologyBioinformaticsCancerMultivariate statisticsMedicineInternal medicineGeneticsComputer scienceMachine learningFerroptosis and cancer prognosisCancer Immunotherapy and BiomarkersCancer-related molecular mechanisms research