In vivo reprogramming of pathogenic lung TNFR2 <sup>+</sup> cDC2s by IFNβ inhibits HDM-induced asthma
Samira Mansouri, Himanshu Gogoi, M. Pipkin, Tiago Machuca, Amir Emtiazjoo, Ashish K. Sharma, Lei Jin
Abstract
cDC2s from patients with emphysema ex vivo. Thus, we identified an IFNβ-specific ERK2-FAO pathway that might be harnessed for DC therapy.
Topics & Concepts
ImmunologyLungHouse dust miteAsthmaReprogrammingMedicineIn vivoEx vivoExacerbationBiologyAllergyAllergenCellInternal medicineBiotechnologyGeneticsImmune Response and InflammationAsthma and respiratory diseasesImmune Cell Function and Interaction