Oxidative stress in genetically triggered thoracic aortic aneurysm: role in pathogenesis and therapeutic opportunities
Stefanie S. Portelli, Brett D. Hambly, Richmond Jeremy, E. Robertson
Abstract
Oxidative stress occurs in genetically triggered TAA, but the precise contribution of ROS to pathogenesis remains incompletely understood. Further research is required to define causative pathological relationships in order to develop therapeutic options.
Topics & Concepts
Oxidative stressPathogenesisMedicineMarfan syndromeThoracic aortic aneurysmAortic aneurysmBicuspid aortic valveAneurysmBioinformaticsPathologicalPathologyInternal medicineSurgeryBiologyAortaAortic Disease and Treatment ApproachesAortic aneurysm repair treatmentsConnective tissue disorders research