CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation
Juan Fernández-García, Fabien Franco, Sweta Parik, Patricia Altea‐Manzano, Antonino Alejandro Pane, Dorien Broekaert, Joke Van Elsen, Giusy Di Conza, Ines Vermeire, Tessa Schalley, Mélanie Planque, Thomas Van Brussel, Rogier Schepers, Elodie Modave, Tobias K. Karakach, Peter Carmeliet, Diether Lambrechts, Ping‐Chih Ho, Sarah‐Maria Fendt
Abstract
T cell differentiation.
Topics & Concepts
EffectorBiologyCD8Cell biologyCellular differentiationCytotoxic T cellT cellPhenotypeGene expressionImmune systemGeneGeneticsIn vitroImmune Cell Function and InteractionT-cell and B-cell ImmunologySingle-cell and spatial transcriptomics