Persistent Transmission of Shigellosis in England Is Associated with a Recently Emerged Multidrug-Resistant Strain of Shigella sonnei
Megan Bardsley, Claire Jenkins, Holly Mitchell, Amy Mikhail, Kate S. Baker, Kirsty Foster, Gwenda Hughes, Timothy J. Dallman
Abstract
Whole-genome sequencing has enhanced surveillance and facilitated detailed monitoring of the transmission of Shigella species in England. We undertook an epidemiological and phylogenetic analysis of isolates from all cases of shigellosis referred to Public Health England between 2015 and 2018 to explore recent strain characteristics and the transmission dynamics of Shigella species. Of the 4,950 confirmed cases of shigellosis identified during this period, the highest proportion of isolates was Shigella sonnei (54.
Topics & Concepts
ShigellosisShigella sonneiTransmission (telecommunications)ShigellaAzithromycinBiologyMicrobiologyVirologyShigella flexneriMedicineAntibioticsGeneticsSalmonellaBacteriaEngineeringEscherichia coliGeneElectrical engineeringEscherichia coli research studiesViral gastroenteritis research and epidemiologyHepatitis Viruses Studies and Epidemiology