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Monocyte to High-Density Lipoprotein Cholesterol Ratio Is Associated with the Presence of Carotid Artery Disease in Acute Ischemic Stroke

Timor Omar, Muammer Karakayalı, Mahmut Yesın, Halil Can Alaydın, Yavuz Karabağ, Ayça Gümüşdağ

2021Biomarkers in Medicine25 citationsDOI

Abstract

Aim: Monocyte to high-density lipoprotein cholesterol ratio (MHR) has recently emerged as a predictor of cardio-cerebrovascular diseases. Since around one-fifth of strokes are linked to atherosclerosis carotid artery, we aimed to present the relationship between carotid artery disease (CAD) and MHR value in acute ischemic stroke (AIS). Materials & methods: A total of 209 adult AIS patients analyzed. Patients divided into two groups in respect to the existence of CAD. MHR was compared between the two groups. Results: MHR with a cut off of 17.23 predicted the presence of disease in the carotid artery, with a sensitivity of 91.9% and specificity of 66.7. MHR was the independent predictor for the presence of disease in the carotid artery. Conclusion: MHR was found to be an independent predictor for the CAD in AIS. Therefore, in AIS patients with high MHR value, CAD should be examined more carefully.

Topics & Concepts

MedicineInternal medicineCardiologyCarotid artery diseaseCarotid arteriesCholesterolStroke (engine)High-density lipoproteinDiseaseCoronary artery diseasePredictive valueMechanical engineeringCarotid endarterectomyEngineeringCerebrovascular and Carotid Artery DiseasesCardiovascular Health and Disease PreventionAcute Ischemic Stroke Management
Monocyte to High-Density Lipoprotein Cholesterol Ratio Is Associated with the Presence of Carotid Artery Disease in Acute Ischemic Stroke | Litcius