Blood pressure and high altitude: physiological response and clinical management
Morin Lang, Grzegorz Bilo, Sergio Caravita, Gianfranco Parati
Abstract
High altitude is an extreme environment that challenges human beings exposed because of work, recreational activities, or habitat. Exposure to hypobaric hypoxia results in physiological adaptations in response to the geography and the associated extreme environmental conditions. These acclimatization responses can be diverse and result from evolutionary changes and comorbidities. In this context, this review aims to identify the available evidence on the effects of high altitude on blood pressurefrom the physiological to clinical aspects at rest and during exerciseand the underlying mechanisms and possible clinical implications of acute and chronic intermittent hypoxia.
Topics & Concepts
MedicineEffects of high altitude on humansHypoxia (environmental)AcclimatizationAltitude (triangle)Context (archaeology)RecreationIntensive care medicineAcute exposureEcologyInternal medicineBiologyChemistryOxygenAnatomyGeometryMathematicsPaleontologyOrganic chemistryHigh Altitude and HypoxiaNeuroscience of respiration and sleepChronic Obstructive Pulmonary Disease (COPD) Research