MiR-21 modulates proliferation and apoptosis of human airway smooth muscle cells by regulating autophagy via PARP-1/AMPK/mTOR signalling pathway
Peng Sun, Shiqing Zhang, Di Wu, Yan Qian, Xinru Xiao, Qian Zhang
Topics & Concepts
AutophagyAMPKPI3K/AKT/mTOR pathwayDownregulation and upregulationPoly ADP ribose polymeraseApoptosisCell biologyCell growthGene silencingPARP inhibitorCancer researchChemistrySignal transductionFOXO3microRNABiologyProtein kinase BProtein kinase AKinasePolymeraseBiochemistryGeneAutophagy in Disease and TherapyMicroRNA in disease regulationPARP inhibition in cancer therapy