A Single “All-in-One” Helper-Dependent Adenovirus to Deliver Donor DNA and CRISPR/Cas9 for Efficient Homology-Directed Repair
Donna Palmer, Dustin L. Turner, Philip Ng
Abstract
applications.
Topics & Concepts
CRISPRCas9BiologyGenome editingGuide RNAIndelHomology directed repairGene targetingGeneticsInduced pluripotent stem cellDNAComputational biologyGeneMolecular biologyDNA repairDNA mismatch repairEmbryonic stem cellSingle-nucleotide polymorphismGenotypeCRISPR and Genetic EngineeringVirus-based gene therapy researchPluripotent Stem Cells Research