The role of ceramide accumulation in human induced pluripotent stem cell-derived cardiomyocytes on mitochondrial oxidative stress and mitophagy
Mohamed M. Bekhite, Andres González-Delgado, Sascha Hübner, P Haxhikadrija, Tom Kretzschmar, Tina Müller, Jasmine M.F. Wu, Tarek Bekfani, Marcus Franz, Maria Wartenberg, Markus H. Gräler, Boris Greber, P. Christian Schulze
Topics & Concepts
MFN2MitophagyPINK1CeramideMitochondrial fissionCell biologymitochondrial fusionBiologyDNM1LLipotoxicityMFN1FIS1Protein kinase BMitochondrionBiochemistryPhosphorylationMitochondrial DNAAutophagyEndocrinologyApoptosisInsulinInsulin resistanceGenePancreatic function and diabetesAutophagy in Disease and TherapySphingolipid Metabolism and Signaling