Litcius/Paper detail

Effects of phytosterol supplementation on lipid profiles in patients with hypercholesterolemia: a systematic review and meta-analysis of randomized controlled trials

Yusi Gao, Ruilong Xun, Jiayue Xia, Hui Xia, Guiju Sun

2023Food & Function25 citationsDOI

Abstract

-nonlinearity = 0.024). Our findings suggest that dietary phytosterols can help reduce TC and LDL-C concentrations in hypercholesterolemia patients without affecting HDL-C and TG concentrations. And the effect may be affected by the food substrate, dose, esterification, intervention cycle and region. The dose of phytosterol is an important factor affecting the level of LDL-C.

Topics & Concepts

PhytosterolMeta-analysisInternal medicineRandomized controlled trialLdl cholesterolLipid profileMedicineCholesterolEndocrinologyFood scienceChemistryCholesterol and Lipid MetabolismLipoproteins and Cardiovascular HealthAtherosclerosis and Cardiovascular Diseases