Knockdown of TRIM32 inhibits tumor growth and increases the therapeutic sensitivity to temozolomide in glioma in a p53-dependent and -independent manner
Yu Cai, Wei Gu, Kang Cheng, Pei Feng Jia, Feng Li, Ming Wang, Wei Feng Zhang, Ji Qiu, Zhe Wu, Wei Guo Zhao
Topics & Concepts
GliomaGene knockdownTemozolomideUbiquitin ligaseDownregulation and upregulationCancer researchApoptosisU87ChemistryCell growthUbiquitinBiologyBiochemistryGeneinterferon and immune responsesCancer Mechanisms and TherapyMicroRNA in disease regulation