JNK signaling contributes to skeletal muscle wasting and protein turnover in pancreatic cancer cachexia
Scott E. Mulder, Aneesha Dasgupta, Ryan J. King, Jaime Abrego, Kuldeep S. Attri, Divya Murthy, Surendra K. Shukla, Pankaj K. Singh
Topics & Concepts
CachexiaWastingMyogenesisMuscle atrophyPancreatic cancerEndocrinologyInternal medicineProtein turnoverC2C12Ubiquitin ligaseSkeletal muscleBiologyMyocytep38 mitogen-activated protein kinasesCancer researchGastrocnemius muscleCancerMAPK/ERK pathwayUbiquitinKinaseMedicineCell biologyBiochemistryGeneProtein biosynthesisMuscle Physiology and DisordersNutrition and Health in AgingGDF15 and Related Biomarkers