Litcius/Paper detail

Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain

Matthew N. Tran, Kristen R. Maynard, Abby Spangler, Louise A. Huuki-Myers, Kelsey D. Montgomery, Vijay Sadashivaiah, Madhavi Tippani, Brianna K. Barry, Dana B. Hancock, Stephanie C. Hicks, Joel E. Kleinman, Thomas M. Hyde, Leonardo Collado‐Torres, Andrew E. Jaffe, Keri Martinowich

2021Neuron236 citationsDOIOpen Access PDF

Topics & Concepts

NeuroscienceNucleus accumbensHuman brainBiologyDorsolateral prefrontal cortexMedium spiny neuronAmygdalaPrefrontal cortexAnterior cingulate cortexCell typeNucleusGABAergicTranscriptomeStriatumCellGene expressionInhibitory postsynaptic potentialDopamineGeneGeneticsCognitionSingle-cell and spatial transcriptomicsNeuroinflammation and Neurodegeneration MechanismsZebrafish Biomedical Research Applications