Sonochemistry in an organocatalytic domino reaction: an expedient multicomponent access to structurally functionalized dihydropyrano[3,2-<i>b</i>]pyrans, spiro-pyrano[3,2-<i>b</i>]pyrans, and spiro-indenoquinoxaline-pyranopyrans under ambient conditions
Biplob Borah, Jahnu Bora, Pambala Ramesh, L. Raju Chowhan
Abstract
Excellent chemical yields have been achieved without using column chromatography. To address the issues of green and more sustainable chemistry, several metrics including Atom Economy (AE), Reaction Mass Efficiency (RME), Atom efficiency, E-factor, Process Mass Intensity (PMI), and Carbon Efficiency (CE) have been quantified for the present methodology that indicates the greenness of the present protocol.
Topics & Concepts
DominoSonochemistryChemistryCatalysisCascade reactionOrganocatalysisReaction conditionsCombinatorial chemistryOrganic chemistryEnantioselective synthesisMulticomponent Synthesis of HeterocyclesSynthesis of Indole DerivativesChemical Synthesis and Reactions