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Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells

Chiwei Peng, Xiang Fu, Kaixuan Wang, Ling Chen, Beijiao Luo, Ni Huang, Yunfeng Luo, Wei Chen

2021European Journal of Pharmacology58 citationsDOI

Topics & Concepts

GPX4Intracerebral hemorrhageNeuroprotectionGlutathione peroxidasePharmacologyGlutathioneGlutathione reductaseOxidative stressGene knockdownMedicinePhospholipid-hydroperoxide glutathione peroxidaseApoptosisLipid peroxidationProgrammed cell deathChemistryBiochemistryInternal medicineEnzymeSubarachnoid hemorrhageFerroptosis and cancer prognosisIntracerebral and Subarachnoid Hemorrhage ResearchRenin-Angiotensin System Studies
Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells | Litcius