On-Surface Azide–Alkyne Cycloaddition Reaction: Does It Click with Ruthenium Catalysts?
Tiexin Li, Essam M. Dief, Zlatica Kalužná, Melanie MacGregor, Cina Foroutan‐Nejad, Nadim Darwish
Abstract
) for the ruthenium-catalyzed reaction is 30% of that measured for the copper-catalyzed 1,4-isomer. The lower conductivity of the 1,5-isomer is confirmed by performing nonequilibrium Green's function computations on relevant model systems. These findings demonstrate the feasibility of ruthenium-based catalysis of surface click reactions and point toward an electrical method for detecting the isomers of click reactions.
Topics & Concepts
RutheniumCatalysisChemistryAlkyneClick chemistryAzideRegioselectivityCycloadditionTriazolePhotochemistryCopperCombinatorial chemistryOrganic chemistryClick Chemistry and ApplicationsMolecular Junctions and NanostructuresAdvanced biosensing and bioanalysis techniques