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Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors

Hao Hu, Fei Chen, Yuhong Dong, Ming Li, Sicong Xu, Mingze Qin, Ping Gong

2020European Journal of Medicinal Chemistry19 citationsDOIOpen Access PDF

Topics & Concepts

HDAC1PharmacophoreIC50Histone deacetylaseHistone deacetylase inhibitorChemistryDocking (animal)Cell cycle checkpointApoptosisCancer cellCell cycleBiochemistryPharmacologyBiologyHistoneCancerIn vitroMedicineGeneticsGeneNursingHistone Deacetylase Inhibitors ResearchPeptidase Inhibition and AnalysisProtein Degradation and Inhibitors
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