Key Considerations for Accurate Exposures in Ecotoxicological Assessments of Perfluorinated Carboxylates and Sulfonates
Justin N. Rewerts, Emerson Christie, A Robel, Todd A. Anderson, Chris McCarthy, Christopher J. Salice, Jennifer A. Field
Abstract
Toxicity reference values for per- and polyfluoroalkyl substances (PFAS) vary even when the same test organism is studied. Although the need to confirm dosing solution concentrations is widely accepted, there are no experimental data to inform best practices when PFAS solutions are prepared. Laboratory data indicate that dissolution time of PFAS solids causes statistically significant deviations between nominal and measured concentrations. Mixing times for select PFAS varied between 2 and 5 h, depending on carbon fluorine chain-length. Environ Toxicol Chem 2021;40:677-688. © 2020 SETAC.
Topics & Concepts
Environmental chemistryOrganismDissolutionEnvironmental scienceDosingChemistryEcotoxicityToxicityBiologyOrganic chemistryPaleontologyPer- and polyfluoroalkyl substances researchToxic Organic Pollutants ImpactAtmospheric chemistry and aerosols