Synthesis and biological evaluation of cholic acid-conjugated oxaliplatin as a new prodrug for liver cancer
Jing Jiang, Fuguo Han, Kaixuan Cai, Qiushuo Shen, Cuiping Yang, Anli Gao, Juan Yu, Xuemei Fan, Yanli Hao, Zhao Wang, Weiping Liu, Yun Shi, Qingfei Liu
Topics & Concepts
OxaliplatinChemistryProdrugCholic acidPharmacologyCytotoxicityLiver cancerCancerCancer researchLinkerIn vitroBiochemistryHepatocellular carcinomaBile acidInternal medicineMedicineColorectal cancerComputer scienceOperating systemMetal complexes synthesis and propertiesDrug Transport and Resistance MechanismsCancer therapeutics and mechanisms