Superoxide anion radical induced phototoxicity of 2,4,5,6-Tetraminopyrimidine sulfate via mitochondrial-mediated apoptosis in human skin keratinocytes at ambient UVR exposure
Saumya Shukla, Deepti Chopra, Sunil Patel, Sandeep Negi, Ajeet K. Srivastav, Ratnasekhar Ch, Lakshmi Bala, Ashish Dwivedi, Ratan Singh Ray
Topics & Concepts
PhototoxicityHaCaTApoptosisSuperoxideCytochrome cChemistryCatalaseHuman skinViability assayDownregulation and upregulationBiochemistryPharmacologyMolecular biologyBiologyAntioxidantIn vitroEnzymeGeneticsGeneSkin Protection and AgingPhotodynamic Therapy Research StudiesSynthesis and biological activity