Copper oxide integrated perylene diimide self-assembled graphitic pencil for robust non-enzymatic dopamine detection
Umay Amara, Sara Riaz, Khalid Mahmood, Naeem Akhtar, Muhammad Nasir, Akhtar Hayat, Muhammad Khalid, Muhammad Yaqub, Mian Hasnain Nawaz
Abstract
), high structural stability, repeatability and excellent reproducibility with an RSD value of 2.9%. Moreover, the developed system showed a wide linear range (5 μM to 500 μM) and reliable selectivity even in the presence of co-existing interferants, such as ascorbic acid and uric acid. The fabricated nanohybrid was eventually employed to analyze DA in spiked physiological fluids and provided satisfactory recoveries. The designed PDI-CuO based interface also showed a very low detection limit of 6 nM (S/N = 3), consequently confirming its suitability for clinical and biological applications.
Topics & Concepts
PeryleneDiimideDopaminePencil (optics)Copper oxideOxideCopperChemistryNanotechnologyMaterials scienceComputer scienceNeuroscienceBiologyPhysicsOrganic chemistryQuantum mechanicsMoleculeElectrochemical sensors and biosensorsConducting polymers and applicationsNeuroscience and Neural Engineering