Astragali radix - Curcumae rhizoma herb pair suppresses hepatocellular carcinoma through EGFR/AKT/mTOR pathway and induces lipid peroxidation-related ferroptosis via HIF-1α/HO-1/GPX4 axis
Chen Wang, Chen-Hao Shi, Hao-Yang Bai, Jun Lü, Hongtao Hu, Yu-Mei Sun, Hang Gao, Hai An, Jiahui Lü, Huajun Zhao, Zhihui Zhu
Topics & Concepts
PI3K/AKT/mTOR pathwayLipid peroxidationTraditional medicineHepatocellular carcinomaProtein kinase BMedicinal herbsHerbChemistryPharmacologyMedicineBiologyApoptosisAntioxidantCancer researchBiochemistryFerroptosis and cancer prognosisInflammasome and immune disordersImmune cells in cancer