DNMT1 regulates miR-20a/TXNIP-mediated pyroptosis of retinal pigment epithelial cells through DNA methylation
Xiaoting Xi, Min Wang, Qianbo Chen, Jia Ma, Junyan Zhang, Yan Li
Topics & Concepts
PyroptosisDNA methylationDNMT1TXNIPGene silencingApoptosisDNA methyltransferaseDownregulation and upregulationMethylationMolecular biologyBiologyRetinal pigment epitheliumCell biologyGene knockdownTransfectionCancer researchProgrammed cell deathRetinalGene expressionCell cultureOxidative stressBiochemistryDNAGeneGeneticsThioredoxinInflammasome and immune disordersOcular Diseases and Behçet’s SyndromeRetinal Diseases and Treatments