Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes
Nicole Bell, Sanket Bhagat, Shanmugam Muruganandan, Ryunhyung Kim, Kailing Ho, Rachel Pierce, Elena Kozhemyakina, Andrew B. Lassar, Laura W. Gamer, Vicki Rosen, Andreia Ionescu
Topics & Concepts
FOXA2ChondrocyteRUNX2Ectopic expressionSOX9Cell biologyCartilageBiologyType II collagenMolecular biologyChemistryTranscription factorInternal medicineEndocrinologyAnatomyCell cultureMedicineGeneGeneticsOsteoarthritis Treatment and MechanismsNF-κB Signaling PathwaysCell Adhesion Molecules Research