Driving GABAergic neurons optogenetically improves learning, reduces amyloid load and enhances autophagy in a mouse model of Alzheimer’s disease
Zijuan Zhang, Ying Jing, Yajing Ma, Dong-Xiao Duan, Bo Li, Christian Hölscher, Cheng Li, Jingwen Wei, Aishe Gao, Lizhi Shang, Feng Tao, Ying Xing
Topics & Concepts
OptogeneticsNeuroscienceGABAergicStimulationAutophagyLocal field potentialNeuroinflammationRhythmPsychologyBiologyMedicineDiseaseInternal medicineBiochemistryInhibitory postsynaptic potentialApoptosisPhotoreceptor and optogenetics researchNeuroscience and Neuropharmacology ResearchNeural dynamics and brain function