Vancomycin‐Functionalized Porphyrinic Metal‐Organic Framework PCN‐224 with Enhanced Antibacterial Activity against <i>Staphylococcus Aureus</i>
Lijian Chen, Yaoyao Liu, Xu Zhao, Xiu‐Ping Yan
Abstract
A vancomycin (Van) modification strategy on a porphyrinic metal-organic framework (MOF) PCN-224 is presented. The obtained Van-PCN-224 gives the combined advantages of porphyrinic MOF and Van with high photosensitive activity and excellent targeted antibacterial activity against Staphylococcus aureus. The features make Van-PCN-224 promising for antimicrobial therapy.
Topics & Concepts
Staphylococcus aureusVancomycinAntimicrobialAntibacterial activityChemistryMicrobiologyBacteriaBiologyOrganic chemistryGeneticsMetal-Organic Frameworks: Synthesis and ApplicationsNanoplatforms for cancer theranosticsCovalent Organic Framework Applications