Durvalumab plus tremelimumab alone or in combination with low-dose or hypofractionated radiotherapy in metastatic non-small-cell lung cancer refractory to previous PD(L)-1 therapy: an open-label, multicentre, randomised, phase 2 trial
Jonathan D. Schoenfeld, Anita Giobbie‐Hurder, Srinika Ranasinghe, Katrina Kao, Ana Lako, Junko Tsuji, Yang Liu, Ryan Brennick, Ryan D. Gentzler, Carrie B. Lee, Joleen M. Hubbard, Susanne M. Arnold, James L. Abbruzzese, Salma K. Jabbour, Nataliya V. Uboha, Kevin L. Stephans, Jennifer M. Johnson, Haeseong Park, Liza C. Villaruz, Elad Sharon, Howard Streicher, Mansoor M. Ahmed, Hayley Lyon, Carrie Cibuskis, Niall J. Lennon, Aashna Jhaveri, Lin Yang, Jennifer Altreuter, Lauren Gunasti, Jason L. Weirather, Raymond H. Mak, Mark M. Awad, Scott J. Rodig, Helen X Chen, Catherine J. Wu, Arta M. Monjazeb, F. Stephen Hodi
Topics & Concepts
DurvalumabMedicineTremelimumabRadiation therapyInternal medicineRefractory (planetary science)OncologyClinical endpointClinical trialLung cancerCancerImmunotherapyIpilimumabAstrobiologyPhysicsNivolumabCancer Immunotherapy and BiomarkersLung Cancer Diagnosis and TreatmentLung Cancer Treatments and Mutations