Litcius/Paper detail

Visual Loss after Platelet-rich Plasma Injection into the Face

Emely Karam, Alexander Gan, Rafael Muci Mendoza, Edwing Martinez, Evlyn Perez

2020Neuro-Ophthalmology30 citationsDOIOpen Access PDF

Abstract

Platelet-rich plasma has become one of the most widely used facial cosmetics fillers. We evaluated four patients treated by cosmetologists with platelet-rich plasma injections who developed irreversible blindness due to iatrogenic occlusion of the ophthalmic artery; immediately after the injection in the glabellar area in three cases and in the nasolabial fold in one case. Early after the injections the fundi of all patients demonstrated central retinal artery and choroidal occlusions. Later, two patients developed retinal pigment dispersion and one of them a pigmented optic disc. The scars on the skin showed similar characteristics in all patients, which could constitute an important marker in the presumptive diagnosis of platelet-rich plasma injection associated complications.

Topics & Concepts

MedicineNasolabial foldPlatelet-rich plasmaScarsCentral retinal arteryRetinalOphthalmologySurgeryPlateletInternal medicineFacial Rejuvenation and Surgery TechniquesDermatologic Treatments and ResearchFacial Nerve Paralysis Treatment and Research