Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease
Jun Ping Quek, Shuang Liu, Zhenzhen Zhang, Yan Li, Elizabeth Yihui Ng, Ying Ru Loh, Alvin W. Hung, Dahai Luo, CongBao Kang
Topics & Concepts
ProteaseNS3ChemistrySmall moleculeDrug discoveryVirologyZika virusActive siteVirusComputational biologyBiochemistryBiologyEnzymeMosquito-borne diseases and controlViral Infections and VectorsInsect symbiosis and bacterial influences