A Newly Identified Group of P-like (PL) Fimbria Genes from Extraintestinal Pathogenic Escherichia coli (ExPEC) Encode Distinct Adhesin Subunits and Mediate Adherence to Host Cells
Hajer Habouria, Hicham Bessaiah, Pravil Pokharel, Sabin Dhakal, Ségolène Maris, Julie Buron, Sébastien Houle, Charles M. Dozois
Abstract
mutant also showed decreased colonization of the kidneys in a mouse competitive infection model. PL fimbriae may represent previously unrecognized adhesins that could contribute to host specificity and tissue tropism of some E. coli strains.
Topics & Concepts
FimbriaBacterial adhesinBiologyEscherichia coliPlasmidPilusGeneMicrobiologyGeneticsEnterobacteriaceaeHost (biology)Vibrio bacteria research studiesMicrobial Community Ecology and PhysiologyEscherichia coli research studies