Nonredundant Dimethyl Sulfoxide Reductases Influence Salmonella enterica Serotype Typhimurium Anaerobic Growth and Virulence
Eva N. Rodríguez‐Cruz, Amanda L. Haeberle, T. L. Westerman, M. E. Durham, M. M. Suyemoto, Leigh A. Knodler, Johanna R. Elfenbein
Abstract
Facultative anaerobic enteric pathogens can utilize a diverse array of alternate electron acceptors to support anaerobic metabolism and thrive in the hypoxic conditions within the mammalian gut. Dimethyl sulfoxide (DMSO) is produced by methionine catabolism and can act as an alternate electron acceptor to support anaerobic respiration.
Topics & Concepts
Salmonella entericaBiologyMicrobiologyEscherichia coliVirulenceDimethyl sulfoxideBiochemistrySalmonellaOperonMutantBacteriaGeneChemistryGeneticsOrganic chemistrySalmonella and Campylobacter epidemiologyVibrio bacteria research studiesEscherichia coli research studies