Ribosomopathy-associated mutations cause proteotoxic stress that is alleviated by TOR inhibition
Carles Recasens-Alvarez, Cyrille Alexandre, Joanna Kirkpatrick, Hisashi Nojima, David J. Huels, Ambrosius P. Snijders, Jean‐Paul Vincent
Topics & Concepts
Cell biologyBiologyMutationGeneticsGeneCRISPR and Genetic EngineeringUbiquitin and proteasome pathwaysEndoplasmic Reticulum Stress and Disease