Comparative effectiveness of combination therapy with nirmatrelvir–ritonavir and remdesivir versus monotherapy with remdesivir or nirmatrelvir–ritonavir in patients hospitalised with COVID-19: a target trial emulation study
Ming Hong Choi, Eric Yuk Fai Wan, Ian Chi Kei Wong, Esther W. Chan, Wing Ming Chu, Anthony Raymond Tam, Kwok Yung Yuen, Ivan Fan Ngai Hung
Topics & Concepts
RitonavirCoronavirus disease 2019 (COVID-19)MedicineEmulationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakVirologyLopinavir/ritonavirPharmacologyHuman immunodeficiency virus (HIV)Viral loadAntiretroviral therapyInternal medicinePsychologyDiseaseSocial psychologyOutbreakInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesPharmacological Receptor Mechanisms and Effects