Oxidative stress and related metabolic alterations are induced in ex situ perfusion of donated hearts regardless of the ventricular load or leukocyte depletion
Sanaz Hatami, Xiao Qi, Mobashir Khan, Keir Forgie, Sayed Himmat, Bryce Tkachuk, Mitchell J. Wagner, Xiuhua Wang, Jayan Nagendran, Darren H. Freed
Topics & Concepts
Oxidative stressMedicineOxidative phosphorylationPerfusionInflammationHeart transplantationIschemiaInternal medicineProinflammatory cytokineTransplantationCardiologyEndocrinologyBiologyBiochemistryTransplantation: Methods and OutcomesMechanical Circulatory Support DevicesCardiac Ischemia and Reperfusion