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A Series of Mono- and Bis-Alkynyl Co(III) Complexes Supported by a Tetra-imine Macrocyclic Ligand (TIM)

Leobardo Rodriguez Segura, Seul Ah Lee, Brandon L. Mash, Ashley J. Schuman, Tong Ren

2021Organometallics15 citationsDOI

Abstract

Reported herein is the synthesis and characterization of a series of mono- and bis-alkynyl CoIII(TIM) complexes, where TIM is 2,3,9,10-tetramethyl-1,4,8,11-tetraazacyclotetradeca-1,3,8,10-tetraene. The trans-[Co(TIM)(C2Ar)Cl]+ type complexes (Ar = phenyl (Ph, 1a), naphthalene (Np, 1b), and -C6F5 (1c)) were prepared by the addition of HC2Ar to trans-[Co(TIM)Cl2]PF6 in the presence of Et3N. Treatment of the mono-alkynyl complexes with AgOTf in MeCN resulted in the trans-[Co(TIM)(C2Ar)(NCMe)](OTf)2 complexes (Ar = Ph (2a), Np (2b), and -C6F5 (2c)). Complexes 2a and 2b react with the respective HC2Ar ligand in the presence of Et3N to afford the symmetrical bis-alkynyl complexes trans-[Co(TIM)(C2Ar)2]+ (Ar = Ph (3a) and Np (3b)). trans-[Co(TIM)(C2C6F5)2]+ (3c) was obtained directly from the prolonged reaction of trans-[Co(TIM)Cl2]PF6 with HC2C6F5. Furthermore, the addition of HC2Ph to 2c in the presence of a weak base yielded the unsymmetrical bis-alkynyl complex trans-[Co(TIM)(C2C6F5)(C2Ph)]OTf (4). Molecular structures of complexes 1a/b, 2a/b, [3a]PF6, 3b, and 4 were established through single crystal X-ray diffraction. The absorption spectra for 1–4 display d–d bands between 380 and 470 nm. Complexes 1b–3b exhibited Np-based fluorescence. Electrochemical studies revealed that all complexes display an irreversible reduction characteristic of the CoIII center, as well as up to two irreversible reduction(s) localized on the TIM macrocycle.

Topics & Concepts

ChemistryLigand (biochemistry)StereochemistryImineCrystal structureMedicinal chemistryCrystallographyCatalysisOrganic chemistryBiochemistryReceptorMetal complexes synthesis and propertiesOrganometallic Complex Synthesis and CatalysisMagnetism in coordination complexes