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Wild-type IDH2 protects nuclear DNA from oxidative damage and is a potential therapeutic target in colorectal cancer

Shuang Qiao, Wenhua Lu, Christophe Glorieux, Jiangjiang Li, Peiting Zeng, Ning Meng, Huiqin Zhang, Shijun Wen, Peng Huang

2021Oncogene27 citationsDOI

Topics & Concepts

IDH2DNA damageBiologyIsocitrate dehydrogenaseCancer researchCancer cellOxidative phosphorylationDNA repairOxidative stressCancerMolecular biologyIDH1BiochemistryMutationDNAGeneticsEnzymeGeneDNA Repair MechanismsGlioma Diagnosis and TreatmentCancer, Hypoxia, and Metabolism
Wild-type IDH2 protects nuclear DNA from oxidative damage and is a potential therapeutic target in colorectal cancer | Litcius