KAT8-mediated MDH2 lactylation promotes renal cancer progression by enhancing mitochondrial function and stress resistance
Yuangui Tang, Chenyun Dai, Huihui Yang, Xian Yang, Ziyu Chen, Jinxiu Dou, Liuxu Zhang, Tao Bai, Junfang Zheng
Topics & Concepts
MitochondrionBiologyCitric acid cycleSIRT3Cell biologyCancer cellCytosolBiochemistryNAD+ kinaseMetabolismCancerEnzymeSirtuinGeneticsCancer, Hypoxia, and MetabolismMitochondrial Function and PathologyEpigenetics and DNA Methylation