Lipid overload impairs hepatic VLDL secretion via oxidative stress-mediated PKCδ-HNF4α-MTP pathway in large yellow croaker (Larimichthys crocea)
Wei Fang, Qiuchi Chen, Kun Cui, Qiang Chen, Xueshan Li, Ning Xu, Kangsen Mai, Qinghui Ai
Topics & Concepts
Microsomal triglyceride transfer proteinSteatosisVery low-density lipoproteinOxidative stressProtein kinase CChemistryInternal medicineHepatocyteReactive oxygen speciesEndocrinologyLipid dropletLipoproteinBiochemistryBiologySignal transductionIn vitroMedicineCholesterolPeroxisome Proliferator-Activated ReceptorsLiver Disease Diagnosis and TreatmentCholesterol and Lipid Metabolism