Aptamer‐Based Cancer Cell Analysis and Treatment
Limei Wu, Yutong Zhang, Zhimin Wang, Yue Zhang, Jianmei Zou, Liping Qiu
Abstract
Aptamers are a class of single-stranded DNA or RNA oligonucleotides that can exclusively bind to various targets with high affinity and selectivity. Regarded as "chemical antibodies", aptamers possess several intrinsic advantages, including easy synthesis, convenient modification, high programmability, and good biocompatibility. In recent decades, many studies have demonstrated the superiority of aptamers as molecular tools for various biological applications, particularly in the area of cancer theranostics. In this review, we focus on recent progress in developing aptamer-based strategies for the precise analysis and treatment of cancer cells.
Topics & Concepts
AptamerOligonucleotideComputational biologyNanotechnologyChemistryDNACombinatorial chemistryComputer scienceBiologyMolecular biologyMaterials scienceBiochemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry