Antibacterial efficacy of low-dosage silver nanoparticle–sodium alginate–chitosan nanocomposite films against pure and clinical acne strains
Bảo Lâm Thái Trần, Thanh Van Vo, Teng-Ping Chu, Dao Bach, Thai Quang Nguyen, P. Luu, V T Tran, Hien Duong, Nhi Hoang Nguyen, Gai Thi Le, Thu Thi Tran, Khanh Tran, Le Thi Cam Tuyen, Truong Ngoc Dinh, Ngo Ngoc Uyen, Thi Thu Tram Nguyen, Ngoc‐Van Thi Nguyen, Kien Trung Nguyen, Thi Nhu Le Tran, Phuoc Huu Le
Abstract
> 0.05) across all strains. Importantly, the AgNPs-Alg-Chi films demonstrated excellent biocompatibility with human keratinocytes (HaCaT cells), maintaining cell viability above 70%. The present AgNPs-Alg-Chi nanocomposite films synthesized by a green approach demonstrated potent antibacterial activity, making them promising for further development into suitable products for human use.
Topics & Concepts
ChitosanNanocompositeSodium alginateAcneNanoparticleSilver nanoparticleAntibacterial activityMaterials scienceNuclear chemistryChemistryChemical engineeringSodiumNanotechnologyOrganic chemistryDermatologyMedicineBacteriaEngineeringGeneticsBiologyAcne and Rosacea Treatments and EffectsSkin Protection and AgingAdvancements in Transdermal Drug Delivery