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The molecular mechanism of temperature-dependent phase separation of heat shock factor 1

Qiunan Ren, Linge Li, Lei Liu, Juan Li, Chaowei Shi, Yujie Sun, Xuebiao Yao, Zhonghuai Hou, ShengQi Xiang

2025Nature Chemical Biology24 citationsDOI

Topics & Concepts

HSF1Heat shockHeat shock factorHeat shock proteinBiophysicsShock (circulatory)Mechanism (biology)ChemistryChemical physicsHsp70ThermodynamicsBiologyPhysicsBiochemistryGeneInternal medicineMedicineQuantum mechanicsHeat shock proteins researchthermodynamics and calorimetric analysesPhysiological and biochemical adaptations
The molecular mechanism of temperature-dependent phase separation of heat shock factor 1 | Litcius