The relationship of tryptophan hydroxylase-2 methylation to early-life stress and its impact on short-term antidepressant treatment response
Tian Shen, Xingyu Li, Lei Chen, Zimu Chen, Tingting Tan, Tiantian Hua, Bingwei Chen, Yonggui Yuan, Zhijun Zhang, Liz Kuney, Zhi Xu
Topics & Concepts
TPH2Tryptophan hydroxylaseAntidepressantDNA methylationInternal medicineMajor depressive disorderCpG siteMethylationEndocrinologyPsychologyMedicineOncologyBiologySerotoninGeneticsAmygdalaGeneGene expressionHippocampusReceptorSerotonergicEpigenetics and DNA MethylationTryptophan and brain disordersMental Health via Writing